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The alternative dates for this week are September 11th through September 17th. On Monday, May 15th thru Friday, May 19th. For paving operations. Rationale: Chronic heroin use can cause deficits in response inhibition, leading to a loss of control over drug use, particularly in the context of drug related cues. Unfortunately, heightened incentive salience and motivational bias in response to drug related cues may exist following abstinence from heroin use.Methods: Sixteen long term (8 24 months) male heroin abstainers and 16 male healthy controls completed a modified two choice oddball paradigm, in which a neutral “chair” picture served as frequent standard stimuli; the neutral and drug related pictures served as infrequent deviant stimuli of different conditions respectively. Event related potentials were compared across groups and conditions.Results: Our results showed that heroin abstainers exhibited smaller N2d amplitude (deviant minus standard) in the drug cue condition compared to the neutral condition, due to smaller drug cue deviant N2 amplitude compared to neutral deviant N2.